WFDC1 Antilichaam - N-terminaal gebied: Biotine (ARP57525 P050-Biotine)

WAP four-disulfide core domain 1

PS20

58189

Q9HC57

NP_067020

Human, Dog

The immunogen is a synthetic peptide directed towards the N terminal region of human WFDC1

This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.

EZR; ZNF677; RAB40B; FOSL1; XRCC2

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Dog: 91%; Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

21kDa

Wet Ice

220

WFDC1

WFDC1

Rabbit

WAP four-disulfide core domain protein 1

NM_021197

WKRALPARLAEKSRAEEAGAPGGPRQPRADRCPPPPRTLPPGACQAARCQ