Win 47338
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Win 47338 (compound 14) is a control compound of inhibitors of the mitotic kinase monopolar spindle MPS1 and Aurora kinases (AurA/AurB) (Ki>100 μM) [1].
80047-24-1
12352005
H302-H315-H319-H335
Aurora Kinase
Cell Cycle/DNA Damage; Epigenetics
Others
O=C(C1=CC(C2=CC=NC=C2)=C(C)NC1=O)N
C12H11N3O2
229.23
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
[1]Fearon D, et al. Synthesis and profiling of a 3-aminopyridin-2-one-based kinase targeted fragment library: Identification of 3-amino-5- (pyridin-4-yl) pyridin-2 (1H) -one scaffold for monopolar spindle 1 (MPS1) and Aurora kinases inhibition. Bioorg Med Chem. 2018 Jul 15;26 (11) :3021-3029.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W100186/
Reference compound1
No Development Reported
Beschrijving
Win 47338 (compound 14) is a control compound of inhibitors of the mitotic kinase monopolar spindle MPS1 and Aurora kinases (AurA/AurB) (Ki>100 μM) [1].
Specificaties
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