WIZ Antilichaam

WIZ Antibody: WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its message was found to be expressed in the granule cell layers of the cerebellum as well as in the dentate gyrus and olfactory bulb. Later analysis indicates however that WIZ is ubiquitously expressed. WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. WIZ can also associate with CtBP family proteins, known to be transcriptional co-repressors, and has been suggested to link G9a/GLP complexes to the CtBP co-repressor machinery, possibly regulating complex stability and gene silencing.

58525

O95785

AAI44333

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

WIZ Antibody is affinity chromatography purified via peptide column.

Cat. No. 1462 - Rat Lung Tissue Lysate

1 mg/mL

WIZ Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

WIZ antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

At least four isoforms of WIZ are known to exist; this antibody will detect all four.

WIZ

Cat. No. 10-301 - Human Brain Tissue Slide

Widely interspaced zinc finger motifs

Homo sapiens

Matsumoto K, Ishii N, Yoshida S, et al. Molecular cloning and distinct developmental expression pattern of spliced forms of a novel zinc finger gene wiz in the mouse cerebellum. Brain Res. Mol. Brain Res.1998; 61:179-89.

Ueda J, Tachibana M, Ikura T, et al. Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP. J. Biol. Chem.2006; 281:20120-8.

WIZ Antibody: ZNF803, ZNF803, Protein Wiz, Widely-interspaced zinc finger-containing protein

ELISA, WB, IHC-P, IF

151301215

Liquid