WKK 2 (Ab 580) Antilichaam

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

5781

Q06124

NP_002825.3

Human, Mouse, Rat

SHP-2 (Ab-580) antibody was raised against a peptide sequence around aa.578~582 (R-V-Y-E-N) derived from Human SHP-2.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

72 kDa

This antibody detects endogenous level of total SHP-2 protein.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

PTPN11

Protein tyrosine phosphatase, non-receptor type 11

Homo sapiens

Ferjoux G, et al. (2003) Mol Biol Cell. 2003; 14 (9) : 3911-3928. Shi ZQ, et al. (2000) Mol Cell Biol ; 20 (5) : 1526-1536. Li C, Friedman JM. (1999) Proc Natl Acad Sci U S A ; 96 (17) : 9677-9682Manes S, et al. (1999) Mol Cell Biol ; 19 (4) : 3125-3135. Oh ES, et al. (1999) Mol Cell Biol; 19 (4) : 3205-3215.

CFC, NS1, SHP2, BPTP3, PTP2C, PTP-1D, SH-PTP2, SH-PTP3, CDX3, Protein-tyrosine phosphatase 2C

WB, IHC, IF

33356177

Liquid