WNK1 (NM 213655) Humaan Recombinant Proteïne

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010]

Purified recombinant protein of Human WNK lysine deficient protein kinase 1 (WNK1), transcript variant 3, Thr104-Ala373, with N-terminal His tag, expressed in E. coli, 50ug

HSAN2; HSN2; KDP; p65; PPP1R167; PRKWNK1; PSK

65125

Q9H4A3

NM_213655

12p13.33

E. coli

N-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Druggable Genome, Protein Kinase

29.2 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

WNK1

Human

NP_998820

https://www.ncbi.nlm.nih.gov/gene/65125

https://www.uniprot.org/uniprot/Q9H4A3

https://www.ncbi.nlm.nih.gov/nuccore/NM_213655

https://www.ncbi.nlm.nih.gov/nuccore/NP_998820