WP1066
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
WP1066 (857064-38-1) is an inhibitor of the JAK2/STAT3 pathway as well as STAT5 and AKT.1,2,3 It downregulated Bcl-XL, Mcl-1, and c-myc while activating Bax and inducing apoptosis.1 Active against human malignant glioma U87-MG (IC50 = 5.6µM) and U373-MG (IC50 = 3.7µM) cells. Enhances T-cell cytotoxicity via inhibition of regulatory T-cells.4,5 WP1066 abrogated PD-L1 expression in lymphoma cell lines.6
Unconjugated
White solid
-20°C
Beschrijving
WP1066 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
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