WWOX Antilichaam

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

51741

Q9NZC7

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human WWOX (NP_057457.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Growth Factors, Neuroscience

Affinity purification

SKOV3

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 46kDa

IgG

WWOX

LO2

HT-29

A-549

Jurkat

Mouse brain

WW domain-containing oxidoreductase

Homo sapiens

WW domain-containing oxidoreductase, 111-, Fragile site FRA16D oxidoreductase, WWOX, FOR, WOX1

WB, IF

Liquid