WWOX (fosfo-Tyr33) Antilichaam

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD) . The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism.

51741

Q96KM3

NP_057457.1

Human, Mouse

WWOX (phospho Tyr33) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 33 (W-V-Y (p) -Y-A) derived from Human WWOX.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

55 kDa

IgG

The antibody detects endogenous levels of WWOX only when phosphorylated at tyrosine 33.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

WWOX

WW domain containing oxidoreductase

Homo sapiens

Bednarek A.K., Cancer Res. 60:2140-2145 (2000) .

Ried K., Hum. Mol. Genet. 9:1651-1663 (2000) .

Bednarek A.K., Cancer Res. 61:8068-8073 (2001) .

FOR, WOX1, Aberrant WW domain-containing oxidoreductase

WB, IHC

7706523

Liquid