WWP2 Antilichaam - middengebied HRP (ARP43088_P050-HRP)

WW domain containing E3 ubiquitin protein ligase 2

AIP2, WWp2-like

11060

O00308

NP_955456

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human WWP2

WWP2 is a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. WWP2 contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions.This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

LGALS9B; ANKRD44; FBXL18; VPS37C; PABPC1; RUSC1; HNRNPUL1; WWP2; PAIP1; TRAF4; FAM189A2; PDLIM7; EIF3A; WIPF1; UBE2L3; UBC; SNRPC; PTCH1; SMAD6; SMAD3; EZH2; PTEN; UBE2D3; FBXL15; RNF11; ARRDC1; ARRDC4; ARRDC3; VPS11; UBE2G1; UBE2J2; UBE2E3; UBE2E1; UBE2D

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

WWP2 is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%; Sheep: 100%; Zebrafish: 80%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

47kDa

Rougier, J.S., Am. J. Physiol., Cell Physiol. 288 (3), C692-C701 (2005)

Wet Ice

431

WWP2

WWP2

Rabbit

NEDD4-like E3 ubiquitin-protein ligase WWP2

NM_199424

EMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYH