WYE-687
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1062161-90-3
C08764-5mg
MTOR
PI3K/Akt/mTOR
COC (=O) NC1=CC=C (C=C1) C2=NC3=C (C=NN3C4CCN (CC4) CC5=CN=CC=C5) C (=N2) N6CCOCC6
C28H32N8O3
WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K (T389) and mTORC2/P-AKT (S473) but no effect observed on P-AKT (T308) . Selectivity for mTOR is greater than PI3Kα (>100-fold) and PI3Kγ (>500-fold) .
2 years -80 in solvent
Beschrijving
WYE-687 Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
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