Xevinapant (AT406)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1071992-99-8
ARRY-334543, Debio1143, SM-406
C17046-200mg
E3 Ligase
Ubiquitin
CC (C) CC (=O) N1CCC2CCC (N2C (=O) C (C1) NC (=O) C (C) NC) C (=O) NC (C3=CC=CC=C3) C4=CC=CC=C4
C32H43N5O4
Xevinapant (AT406, ARRY-334543, Debio1143, SM-406) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.
2 years -80 in solvent
Beschrijving
Xevinapant (AT406) Beschikbaar in 200 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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