XPA Antibody - C-terminal regio : HRP (ARP61208 P050-HRP)

Xeroderma pigmentosum, complementation group A

XP1, XPAC

7507

P23025

NP_000371

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.

NDEL1; TRIM27; HERC2; ATR; PRKDC; ATM; HMGB1; ERCC1; DDB2; DDB1; RPA1; XPC; POLR2A; HHV8GK18_gp81; GTF2H1; ERCC6; RPA2; MSH3; MSH2; XAB2; GPN1; RPA4; RASSF1; GTF2E2; EP300

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

31kDa

Wet Ice

273

XPA

XPA

Rabbit

DNA repair protein complementing XP-A cells

NM_000380

MKQKKFDKKVKELRRAVRSSVWKRETIVHQHEYGPEENLEDDMYRKTCTM