XRCC1 Mouse Monoclonal Antibody [Kloon ID: LBI2F8]

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Carrier-free (BSA/glycerol-free) XRCC1 mouse monoclonal antibody, clone LBI2F8

RCC

Homo sapiens X-ray repair cross complementing 1 (XRCC1), mRNA.

7515

P18887

Unconjugated

Base excision repair

Base excision repair

WB 1:2000, IHC 1:50, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

XRCC1

https://www.ncbi.nlm.nih.gov/gene/?term=7515

https://www.uniprot.org/uniprot/P18887