XRCC4 Mouse Monoclonal Antibody [Kloon ID: LBI4H9]

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants.

Carrier-free (BSA/glycerol-free) XRCC4 mouse monoclonal antibody, clone LBI4H9

SSMED

Homo sapiens X-ray repair cross complementing 4 (XRCC4), transcript variant 3, mRNA.

7518

Q13426

Unconjugated

Non-homologous end-joining

Non-homologous end-joining

WB 1:2000, IHC 1:50

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

XRCC4

https://www.ncbi.nlm.nih.gov/gene/?term=7518

https://www.uniprot.org/uniprot/Q13426