XRCC5 Antilichaam

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

7520

P13010

Human

Recombinant fusion protein containing a sequence corresponding to amino acids 540-732 of human XRCC5 (NP_066964.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 83kDa

IgG

XRCC5

A-549

X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

Homo sapiens

XRCC5, KU80, KUB2, Ku86, NFIV, KARP1, KARP-1

WB, IHC

Liquid