XRCC5/Ku80 Polyklonale Antilichaam

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

XRCC5; Ku80; TLAA; CTC85; Ku86; CTCBF; G22P2; KARP1; FLJ39089; KARP-1; NFIV; KU80; KUB2; EC 3.6.1.

7520

Nucleus

Others

301-450/732

XRCC5/Ku80

Unconjugated

KLH conjugated synthetic peptide derived from human Ku-80

WB, ELISA, IHC-P, IHC-F, IF

Purified by Protein A.

1µg/µl

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

7520

Human