YAP1 Antilichaam, KO gevalideerd

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

10413

P46937

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1 (NP_001123617.1) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Cancer, Cell Cycle, Signal Transduction, Transcription

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 72kDa

IgG

YAP1

LO2

BT-474

A549

Yes-associated protein 1

Homo sapiens

YAP1, YAP, YAP2, YAP65, YKI

WB, IHC, IF, IP

Liquid