YB1 (fosfo Ser102) Antilichaam

YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs) . Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A) n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.

4904

P67809

NP_004550.2

Human, Mouse, Rat

YB1 (phospho Ser102) antibody was raised against a peptide sequence around phosphorylation site of Serine 102 (L-R-S (p) -V-G) derived from Human YB1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

36 kDa

IgG

The antibody detects endogenous levels of YB1 only when phosphorylated at serine 102.

Western Blot: 1:500~1:1000

YBX1

Y box binding protein 1

Homo sapiens

Sakura H., Gene 73:499-507 (1988) .

Didier D.K. Proc. Natl. Acad. Sci. U.S.A. 85:7322-7326 (1988) .

Kolluri R., Nucleic Acids Res. 19:4771-4771 (1991) .

CBF-A, NSEP1, EFI-A, MSY-1, YBX1

WB

34098946

Liquid