YBX2 Antilichaam

YBX2 Antibody: Germ cell specific Y-box binding protein (YBX2), a germ-cell-specific member of the Y-box family of DNA-/RNA-binding proteins, is a major constituent of messenger ribonucleoprotein particles (mRNPs) and involved in the regulation of the stability and/or translation of germ cell mRNAs. It is proposed to function as a coactivator of transcription in the nucleus and to stabilize and store maternal and paternal mRNAs in the cytoplasm. YBX2 binds to the Y-box consensus promoter element and is expressed in oocytes and testicular germ cells in the stage of spermatogonia to spermatocyte. Recent studies show that deletion of YBX2 leads to the disruption of both spermatogenesis and oogenesis.

51087

Q9Y2T7

NP_057066

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell

YBX2 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1313 - Human Testis Tissue Lysate

1 mg/mL

YBX2 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

YBX2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

YBX2

Cat. No. 11-701 - Human Testis Tissue Slide

Y box binding protein 2

Homo sapiens

Kohno Y, Matsuki Y, Tanimoto A, et al. Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen. Br. J. Cancer2006; 94:710-6.

Medvedev S, Yang J, Hecht NB, et al. CDC2A (CDK1) -mediated phosphorylation of MSY2 triggers maternal mRNA degradation during mouse oocyte maturation. Dev. Biol.2008; 321:205-15.

Yang J, Medvedev S, Yu J, et al. Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility. Proc. Natl. Acad. Sci. USA2005; 102:5755-60.

Hammoud S, Emery BR, and Dunn D. Sequence alterations in the YBX2 gene are associated with male factor infertility. Fertil. Steril.2009; 91:1090-5.

YBX2 Antibody: DBPC, MSY2, CSDA3, CONTRIN, Y-box-binding protein 2, Contrin, Dbpc

ELISA, WB, IHC-P, IF

156415990

Liquid