(Z) 2S,4R-sacubitril (Standaard)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
(Z) 2S,4R-Sacubitril (Standard) is the analytical standard of (Z) 2S,4R-Sacubitril. This product is intended for research and analytical applications. (Z) 2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
2751722-77-5
12352005
Drug Metabolite; Reference Standards
Metabolic Enzyme/Protease; Others
Cardiovascular Disease
[H]N(C(/C=C\C(O)=O)=O)[C@H](CC(C=C1)=CC=C1C2=CC=CC=C2)C[C@@H](C)C(OCC)=O
C24H27NO5
409.47
[1]Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44 (4) :554-9.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-Z0075R/
Reference Standards
Beschrijving
(Z) 2S,4R-Sacubitril (Standard) is the analytical standard of (Z) 2S,4R-Sacubitril. This product is intended for research and analytical applications. (Z) 2S,4R
Specificaties
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