(Z) -Zolucatetide

(Z) -Zolucatetide ((Z) -FOG-001; I-67), a structural isomer of Zolucatetide , is a potent β-catenin inhibitor with an IC50 of.

(Z) -FOG-001; I-67

12352209

β-catenin

Stem Cell/Wnt

Cancer-programmed cell death

Cancer

98.19

DMSO : 100 mg/mL (ultrasonic)

O=C(N[C@@H](CC1=CSC2=C1C=CC=C2)C(N[C@@H](CCC(NCCCC[C@H](NC([C@@H](NC([C@H](C)NC(C(C)(C)NC([C@H](CC3=CC=CC(C(O)=O)=C3)NC([C@@H](N4)CC(O)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)C6=O)=O)C(N[C@H](C(N)=O)C)=O)=O)[C@H](CC7=CSC=C7)NC([C@@]8(CCN(C(OCCC/C=C\CCC[C@](NC([C@H](CC(C)(C)C)NC([C@H](CC(O)=O)N9)=O)=O)(CCC/C=C\C[C@]%10(CCCN%10C(C)=O)C9=O)C4=O)=O)C8)N6)=O

C102H134N18O25S2

2076.39

[1]Brian Halbert WHITE, et al. Stapled peptides and methods thereof. WO2022261257A1.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P10925A/Z-Zolucatetide-SDS-MedChemExpress.pdf

Peptides

No Development Reported