Zapotin

Zapotin is a member of the polymethoxyflavones, which are natural polyphenols from the group of flavonoid. Zapotin exhibits antidepressant, anticancer, antifungal, and antioxidant activity. Zapotin is a chemopreventive and chemotherapeutic agent. Zapotin can result in a reduction of large aberrant crypt foci in CF-1 mouse model. Zapotin inhibits autophagosome formation. Zapotin has inhibitory activity in mouse mammary organ culture with an IC50 of 50 µg/mL[1].

14813-19-5

12352005

H302-H315-H319-H335

Biochemical Assay Reagents; Fungal; Reactive Oxygen Species (ROS)

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Cancer; Infection; Metabolic Disease; Neurological Disease

COC1=CC=C2OC(C3=C(C=CC=C3OC)OC)=CC(C2=C1OC)=O

C19H18O6

342.34

P261-P280-P302+P352

[1]Strawa, J. W., et al., (2021) . Zapotin, a Polymethoxyflavone, with Potential Therapeutic Attributes. International journal of molecular sciences, 22 (24), 13227.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W665208/

Reference compound1

No Development Reported