ZBED3 Antilichaam

ZBED3 Antibody: Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.

84327

Q96IU2

NP_115743

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

ZBED3 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1288 - A20 Cell Lysate

1 mg/mL

ZBED3 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ZBED3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.

ZBED3

Zinc finger, BED-type containing 3

Homo sapiens

Chen T, Li M, Ding Y, et al. Identification of Zinc-finger BED domain containing 3 (Zbed3) as a novel axin-interacting protein that activates Wnt/b-catenin signaling. J. Biol. Chem.2009; 284:6683-9.

ZBED3 Antibody: Zinc finger BED domain-containing protein 3, Axin-interacting protein

ELISA, WB

14150185

Liquid