ZBTB48 Polyklonale Antilichaam

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 48 (ZBTB48), also known as Kruppel-related zinc finger protein 3 or HKR3, is a 688 amino acid member of the Kr_ppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB48 is expressed in the adrenal gland and neuroblastoma cell lines. ZBTB48 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB48 functions as a transcription regulator.

0610011D15Rik; AI327031; GLI Kruppel family member HKR3; HKR3; Krueppel related zinc finger protein 3; Krueppel-related zinc finger protein 3; OTTMUSP00000031803; pp9964; Protein HKR3; RP23-445E20.3; ZBT48_HUMAN; ZBTB 48; Zbtb48; Zinc finger and BTB domain containing 48; Zinc finger and BTB domain containing protein 48; Zinc finger and BTB domain-containing protein 48; Zinc finger protein 855; ZNF855.

3104

Nucleus

451-550/688

ZBTB48

Unconjugated

KLH conjugated synthetic peptide derived from human ZBTB48/ZNF855

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

1µg/µl

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

3104

Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit