ZC3H12A (CT) Peptide

ZC3H12A Antibody: ZC3H12A is an MCP1 (CCL2; MIM 158105) -induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis. ZC3H12A inhibits the Wnt/beta-catenin signaling pathway activity and modulates epithelial-mesenchymal transition during clear cell renal cell carcinoma progression by targeting miRNAs. ZC3H12A ribonuclease can bind and cleave AURKA mRNA in MYCN-amplified neuroblastoma cells. ZC3H12A is a novel link between diabetogenic conditions and impaired insulin secretory capacity. ZC3H12A overexpression in human neuroblastoma cell lines causes cell-cycle arrest by G1/S checkpoint block.

80149

Q5D1E8

Q5D1E7.2

Peptides

200 ug/mL

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Blue Ice

Store SARS-CoV-2 (COVID-19) Spike Q493R G496S Q498R N501Y Y505H Peptide (Omicron) at -20˚ C, stable for one year.

ZC3H12A (CT) Peptide is used for blocking the activity of ZC3H12A (CT) Antibody.

Zinc finger CCCH-type containing 12A

Homo sapiens

Gorka et al. Oncogene. 2021; 40 (50) :6720-6735

Nowak et al. RNA Biol. 2021; 18 (1) :144-156

Tyka et al. Biochim Biophys Acta Mol Basis Dis. 2021; 1867 (10) :166199

Boratyn et al. J Cell Biochem. 2020; 121 (5-6) ;3406-3425

ZC3H12A Antibody: Endoribonuclease ZC3H12A, Monocyte chemotactic protein-induced protein 1, MCP-induced protein 1, MCPIP-1, Zinc finger CCCH domain-containing protein 12A

Blocking

Human

190485853

Liquid