ZCRB1 Antilichaam

ZCRB1 Antibody: ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.

85437

Q8TBF4

NP_149105

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

ZCRB1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1207 - Raji Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

ZCRB1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ZCRB1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

ZCRB1

Zinc finger CCHC-type and RNA binding motif 1

Homo sapiens

Wang H, Gao MX, Li L, et al. Isolation, expression, and characterization of the human ZCRB1 gene mapped to 12q2. Genomics2007; 89:59-69.

Trivedi AK, Bararia D, Christopeit M, et al. Proteomic identification of C/EBP-DBD multiprotein complex: JNK1 activates stem cell regulator C/EBPalpha by inhibiting its ubiquitination. Oncogene2007; 1789-801.

Will CL, Schneider C, Hossbach M, et al. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA2004; 10:929-41.

ZCRB1 Antibody: MADP1, RBM36, MADP-1, SNRNP31, ZCCHC19, Zinc finger CCHC-type and RNA-binding motif-containing protein 1

ELISA, WB

51243065

Liquid