ZD-6169
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ZD-2767 is a selective ATP-sensitive potassium channel agonist. ZD-276 reduces cell membrane excitability and contractility by activating KATP channels in bladder smooth muscle. ZD-2767 is promising for research of overactive bladder[1].
147696-46-6
12352005
Potassium Channel
Membrane Transporter/Ion Channel
Endocrinology
O=C(NC1=CC=C(C(C2=CC=CC=C2)=O)C=C1)[C@](C)(O)C(F)(F)F
C17H14F3NO3
337.29
[1]Fryer RM, et al. (-) - (9S) -9- (3-Bromo-4-fluorophenyl) -2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8 (4H) -one 1,1-dioxide (A-278637), a novel ATP-sensitive potassium channel opener: hemodynamic comparison to ZD-6169, WAY-133537, and nifedipine in the anesthetized canine. J Cardiovasc Pharmacol. 2004 Aug;44 (2) :137-47.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19185/
Reference compound1
Phase 2
Beschrijving
ZD-2767 is a selective ATP-sensitive potassium channel agonist. ZD-276 reduces cell membrane excitability and contractility by activating KATP channels in bladd
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