Zebrafish Acadm Antilichaam / Mcad

ACADM (acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain) is a gene that provides instructions for making an enzyme called acyl-coenzyme A dehydrogenase that is important for breaking down (degrading) a certain group of fats called medium-chain fatty acids. This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Western blot: 0.5-1 µg/mL

A2CG95

Zebrafish

A synthetic peptide corresponding to a sequence at the C-terminus of zebrafish Acadm protein was used as the immunogen for the Zebrafish Acadm antibody.

WB

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Acadm antibody is available for research use only.

After reconstitution, the Zebrafish Acadm antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Acadm antibody should be determined by the researcher.

Western blot analysis of Acadm protein using Zebrafish Acadm antibody and 1) zebrafish head, 2) female zebrafish viscera, 3) male zebrafish viscera, 4) whole zebrafish and 5) zebrafish embryo tissue lysate. Predicted molecular weight ~46 kDa.