Zebrafish c-Myb Antilichaam / Myb

During zebrafish embryogenesis, c-Myb is expressed in the dorsal aorta, where hematopoietic stem cells first emerge, as well as in the developing thymus and other hematopoietic tissues. It regulates the expression of genes involved in cell proliferation, differentiation, and survival. Loss of c-Myb function leads to defects in blood cell development, particularly in the production of lymphoid and myeloid lineages. Due to its conserved function in vertebrate hematopoiesis, zebrafish c-Myb is commonly used in research focused on blood development, leukemia, stem cell biology, and gene regulation. Its accessibility in zebrafish models allows for detailed in vivo studies of hematopoietic disorders and drug screening applications.

Western Blot: 0.5-1 µg/mL

F1QP25, F1QP24

Zebrafish

E. coli-derived zebrafish C-myb recombinant protein (amino acids M1-I590) was used as the immunogen for the Zebrafish C-myb antibody.

WB

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish C-myb antibody is available for research use only.

After reconstitution, the Zebrafish C-myb antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish C-myb antibody should be determined by the researcher.

Western blot analysis of c-Myb protein using Zebrafish c-Myb antibody and zebrafish head tissue lysates. Predicted molecular weight ~67 kDa and ~72 kDa (two isoforms) .