Zebrafish Cyp17a1 Antilichaam

Cyp17a1 is predominantly expressed in steroidogenic tissues such as the interrenal gland, gonads, and brain. During development, it is required for the proper formation of the endocrine system and plays a vital role in processes such as stress regulation, sexual differentiation, and reproduction. By controlling the production of hormones like cortisol, testosterone, and estradiol, Cyp17a1 supports a wide range of physiological functions including metabolism, immune regulation, and fertility. Because of its conserved enzymatic role and tissue-specific expression, zebrafish Cyp17a1 is frequently used as a model to study endocrine system development, steroid hormone biosynthesis, and the impact of environmental or pharmaceutical compounds on hormone production. It is also valuable for research into adrenal and gonadal disorders.

Immunohistochemistry (FFPE) : 2-5 µg/mL

B3DH80

Zebrafish

E. coli-derived zebrafish Cyp17a1 recombinant protein (amino acids Q67-C519) was used as the immunogen for the Zebrafish Cyp17a1 antibody.

IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Cyp17a1 antibody is available for research use only.

After reconstitution, the Zebrafish Cyp17a1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Cyp17a1 antibody should be determined by the researcher.

Membrane

IHC staining of zebrafish Cyp17a1 protein using Zebrafish Cyp17a1 antibody, HRP-labeled secondary and DAB substrate. Cyp17a1 was detected in a paraffin-embedded section of zebrafish spinal cord tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.