Zebrafish Fshb Antilichaam / Follikelstimulerend hormoon beta

Zebrafish Fshb plays a crucial role in the development and maturation of gametes, particularly in promoting folliculogenesis in females and spermatogonial proliferation in males. Its expression and secretion are primarily regulated by gonadotropin-releasing hormone (GnRH) and modulated by feedback from sex steroids and other endocrine factors within the hypothalamic-pituitary-gonadal (HPG) axis. During zebrafish development, fshb expression becomes evident post-embryonically and increases with sexual maturation. Functional studies have shown that Fshb is essential for early-stage follicle development and the onset of puberty, while also contributing to basal steroidogenesis in the gonads. Given the genetic accessibility and transparency of zebrafish, the fshb gene and its protein product are commonly used in reproductive biology, toxicology, and endocrine disruption studies. Zebrafish Fshb shares structural and functional homology with its mammalian counterparts, making it a valuable model for exploring conserved mechanisms of vertebrate reproduction.

Western Blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

Q6TCF7

Zebrafish

E. coli-derived zebrafish Fshb recombinant protein (amino acids E19-H130) was used as the immunogen for the Zebrafish Fshb antibody.

WB, IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Fshb antibody is available for research use only.

After reconstitution, the Zebrafish Fshb antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Fshb antibody should be determined by the researcher.

IHC staining of FFPE zebrafish eye tissue with Zebrafish Fshb antibody, HRP-labeled secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.