Zebrafish Glucocorticoïdenreceptor Antilichaam / Gr / Nr3c1

The zebrafish glucocorticoid receptor is expressed in a wide range of tissues including the brain, liver, muscle, and developing endocrine organs. Upon binding to glucocorticoids, the receptor translocates to the nucleus where it binds specific DNA sequences and modulates the transcription of target genes involved in maintaining homeostasis under stress conditions. It also influences cell differentiation, energy balance, and the inflammatory response. In zebrafish embryos, activation or disruption of glucocorticoid signaling affects key developmental processes such as axis formation, organ maturation, and behavioral programming. Because zebrafish produce cortisol as their primary glucocorticoid, they serve as a powerful model for investigating hormone signaling and endocrine regulation in vertebrates. The glucocorticoid receptor in zebrafish is widely used in research on stress physiology, neuroendocrine development, immune modulation, and environmental toxicology. It is also a valuable target in studies examining the effects of synthetic glucocorticoids and endocrine disrupting compounds.

Western Blot: 0.5-1 µg/mL

Q1XHK0

Zebrafish

E. coli-derived zebrafish Glucocorticoid receptor recombinant protein (amino acids M1-K746) was used as the immunogen for the Zebrafish Glucocorticoid receptor antibody.

WB

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Glucocorticoid receptor antibody is available for research use only.

After reconstitution, the Zebrafish Glucocorticoid receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Glucocorticoid receptor antibody should be determined by the researcher.

Western blot analysis of Glucocorticoid receptor protein using Zebrafish Glucocorticoid receptor antibody and zebrafish head tissue lysates.