Zebrafish Grin1 Antilichaam / Grin1a / Grin1b / Nmdar1.1

Glutamate [NMDA] receptor subunit zeta-1 is a protein that in humans is encoded by the GRIN1 gene. The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

Immunohistochemistry (FFPE) : 2-5 µg/mL

F1R366

Zebrafish

A synthetic peptide corresponding to a sequence at the C-terminus of zebrafish Grin1a/b was used as the immunogen for the Zebrafish Grin1 antibody. This antibody will detect isoforms a & b.

IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Grin1 antibody is available for research use only.

After reconstitution, the Zebrafish Grin1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Grin1 antibody should be determined by the researcher.

Cell membrane

Immunohistochemical analysis of Grin1a/b protein using Zebrafish Grin1 antibody and paraffin-embedded zebrafish brain tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.