Zebrafish Hand2 Antilichaam / Hart en neurale kam derivaten uitgedrukt 2

During early zebrafish embryogenesis, Hand2 is expressed in the lateral plate mesoderm and contributes to the specification and differentiation of cardiac progenitor cells. It is particularly important for the formation of the heart tube and for the development of the atrial and ventricular chambers. Hand2 also regulates the migration and function of neural crest cells, which give rise to structures such as the jaw and pharyngeal arches. Loss of Hand2 function in zebrafish leads to severe defects in heart formation, including impaired looping and chamber development, as well as abnormalities in craniofacial structures. Because of its conserved role in vertebrate development, zebrafish Hand2 is widely used as a model for studying congenital heart defects, craniofacial malformations, and the genetic pathways that guide mesodermal and neural crest cell differentiation. Zebrafish Hand2 is a valuable tool in developmental biology, regenerative medicine, and disease modeling, particularly in research focused on cardiac development and structural birth defects.

Immunohistochemistry (FFPE) : 2-5 µg/mL

P57102

Zebrafish

E. coli-derived zebrafish Hand2 recombinant protein (amino acids M1-Q208) was used as the immunogen for the Zebrafish Hand2 antibody.

IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Hand2 antibody is available for research use only.

After reconstitution, the Zebrafish Hand2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Hand2 antibody should be determined by the researcher.

IHC staining of zebrafish Hand2 protein using Zebrafish Hand2 antibody, HRP-labeled secondary and DAB substrate. Hand2 was detected in a paraffin-embedded section of zebrafish colon tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.