Zebrafish Hdac1 Antilichaam / Histone deacetylase 1

Histone deacetylase 1 is an enzyme that is encoded by the HDAC1 gene. Histone acetylation and deacetylation, catalyzed by multi-subunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. Furukawa et al. (1996) mapped RPD3L1 to 1p34.1 by fluorescence in situ hybridization.

Immunohistochemistry (FFPE) : 2-5 µg/mL

A0A2R8QIW0

Zebrafish

A synthetic peptide corresponding to a sequence in the middle region of zebrafish Hdac1 was used as the immunogen for the Zebrafish Hdac1 antibody.

IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Hdac1 antibody is available for research use only.

After reconstitution, the Zebrafish Hdac1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Hdac1 antibody should be determined by the researcher.

Immunohistochemical analysis of Hdac1 protein using Zebrafish Hdac1 antibody and paraffin-embedded zebrafish brain tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.