Zebrafish Hnrnpa1 Antilichaam / Isoforms a & b

Heterogeneous nuclear ribonucleoprotein A1 is a protein that in humans is encoded by the HNRNPA1 gene. This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.

Immunohistochemistry (FFPE) : 2-5 µg/mL

Q7SXQ3, Q803K3

Zebrafish

An E.coli-derived zebrafish Hnrnpa1a/b recombinant protein (amino acids E10-D43) was used as the immunogen for the Zebrafish Hnrnpa1 antibody. This antibody will detect the a and b isoforms.

IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Hnrnpa1 antibody is available for research use only.

After reconstitution, the Zebrafish Hnrnpa1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Hnrnpa1 antibody should be determined by the researcher.

Immunohistochemical analysis of Hnrnpa1a/b protein using Zebrafish Hnrnpa1 antibody and paraffin-embedded zebrafish colon tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.