Zebrafish Mcm4 Antilichaam

In zebrafish (Danio rerio), mcm4 is a highly conserved gene with critical roles during early embryogenesis and cell proliferation. Expression of mcm4 is enriched in rapidly dividing tissues and during periods of intense developmental activity, reflecting its importance in genome stability and cell cycle progression. Zebrafish models deficient in Mcm4 function have been used to study mechanisms of DNA replication stress, genomic instability, and the cellular response to DNA damage. Additionally, because of its conservation and similarity to human MCM4, zebrafish serves as a useful system for modeling MCM-related human disorders, such as Meier-Gorlin syndrome and cancer predisposition syndromes linked to replication licensing defects. The zebrafish MCM4 protein is a valuable tool for investigating DNA replication dynamics, cell cycle regulation, and the molecular basis of developmental and proliferative diseases.

Western blot: 0.5-1 µg/mL

Q6NZV2

Zebrafish

An E.coli-derived zebrafish Mcm4 recombinant protein (amino acids M343-I659) was used as the immunogen for the Zebrafish Mcm4 antibody.

WB

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Mcm4 antibody is available for research use only.

After reconstitution, the Zebrafish Mcm4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Mcm4 antibody should be determined by the researcher.

Western blot analysis of Mcm4 protein using Zebrafish Mcm4 antibody and zebrafish embryo tissue lysate. The predicted molecular weight of MCM4 is ~97 kDa.