Zebrafish Mmp9 Antilichaam / Matrix metalloproteïnase 9

Mmp9 functions by degrading components of the extracellular matrix such as collagen and gelatin, allowing for tissue restructuring and cell migration. Its expression is tightly regulated and often induced by injury, infection, or developmental cues. In zebrafish, Mmp9 is notably upregulated in response to fin amputation and participates in the regeneration process by clearing damaged matrix and enabling cell proliferation. In the immune system, zebrafish Mmp9 is expressed in neutrophils and macrophages and contributes to leukocyte recruitment and inflammation resolution. It is also involved in remodeling of the brain and other organs during development and in response to environmental stressors. Due to its conservation across vertebrate species, zebrafish Mmp9 serves as a powerful model for studying matrix dynamics, regenerative biology, and inflammatory diseases. It is commonly used in genetic and chemical screens to explore pathways related to tissue remodeling and immune function.

Immunohistochemistry (FFPE) : 2-5 µg/mL

Q7T317

Zebrafish

E. coli-derived zebrafish Mmp9 recombinant protein (amino acids D33-L680) was used as the immunogen for the Zebrafish Mmp9 antibody.

IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Mmp9 antibody is available for research use only.

After reconstitution, the Zebrafish Mmp9 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Mmp9 antibody should be determined by the researcher.

Cytoplasmic, nuclear, secreted

IHC staining of zebrafish Mmp9 protein using Zebrafish Mmp9 antibody, HRP-labeled secondary and DAB substrate. Mmp9 was detected in a paraffin-embedded section of zebrafish muscle tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.