Zebrafish Myca Antibody / Myc-A / c-Myc- A

Myc A functions by forming heterodimers with other transcriptional regulators and binding to specific DNA sequences to activate or repress target genes. It promotes the expression of genes involved in cell cycle progression, protein synthesis, and energy metabolism, while also modulating genes associated with apoptosis and cellular stress responses. This makes Myc A critical for balancing growth signals with environmental and developmental cues. During zebrafish development, Myc A is expressed in proliferative regions such as the brain, somites, and hematopoietic tissues. Its expression is tightly regulated to ensure proper tissue formation and to prevent excessive or disorganized cell growth. Dysregulation of Myc A can lead to developmental abnormalities and has been linked to tumor formation in zebrafish models, making it a valuable tool in cancer biology research. Because of its strong conservation across vertebrates and its fundamental role in transcriptional control, zebrafish Myc A is widely used in studies of developmental genetics, stem cell function, oncogenesis, and metabolic regulation.

Western Blot: 0.5-1 µg/mL

P52160

Zebrafish

E. coli-derived zebrafish Myca recombinant protein (amino acids K21-H419) was used as the immunogen for the Zebrafish Myca antibody.

WB

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Myca antibody is available for research use only.

After reconstitution, the Zebrafish Myca antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Myca antibody should be determined by the researcher.

Western blot analysis of Myca protein using Zebrafish Myca antibody and 1) zebrafish head, 2) whole female zebrafish, 3) whole male zebrafish and 4) zebrafish embryo tissue lysate. Predicted molecular weight ~48 kDa.