Zebrafish Neuropeptide Y Antilichaam / Npy

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi.

Immunohistochemistry (FFPE) : 2-5 µg/mL

Q9I8P3

Zebrafish

E. coli-derived zebrafish Neuropeptide Y recombinant protein (amino acids G28-Q62) was used as the immunogen for the Zebrafish Neuropeptide Y antibody.

IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Neuropeptide Y antibody is available for research use only.

After reconstitution, the Zebrafish Neuropeptide Y antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Neuropeptide Y antibody should be determined by the researcher.

Cytoplasmic & secreted

IHC staining of zebrafish Neuropeptide Y protein using Zebrafish Neuropeptide Y antibody, HRP-labeled secondary and DAB substrate. Neuropeptide Y was detected in a paraffin-embedded section of zebrafish kidney tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.