Zebrafish Rcc2 Antilichaam / Proteïne RCC2 homolog

Zebrafish Rcc2 is an ortholog of the human RCC2 protein and shares significant sequence and functional similarity. In both species, Rcc2 functions as part of the chromosomal passenger complex and contributes to the accurate distribution of chromosomes during mitosis. Disruption of Rcc2 function can impair cell division and affect developmental processes, making it a key protein for studies of cell proliferation and morphogenesis. Research on zebrafish Rcc2 is valuable for understanding its conserved roles in cell cycle regulation and cytoskeletal rearrangements. Zebrafish models allow for the exploration of Rcc2 function during embryogenesis, where rapid and precise cell division is essential for normal development. Antibodies targeting zebrafish Rcc2 protein are important tools for studying mitosis, cytoskeletal organization, and related signaling pathways. The orthology between zebrafish Rcc2 and human RCC2 supports the use of zebrafish as a model to investigate fundamental mechanisms of cell division and to study pathways that may be altered in diseases such as cancer.

Western Blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

Q6NYE2

Zebrafish

E. coli-derived zebrafish Rcc2 recombinant protein (amino acids K266-L495) was used as the immunogen for the Zebrafish Rcc2 antibody.

WB, IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Rcc2 antibody is available for research use only.

After reconstitution, the Zebrafish Rcc2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Rcc2 antibody should be determined by the researcher.

Cytoplasm, cell membrane, nuclear

IHC staining of FFPE zebrafish spinal cord tissue with Rcc2 antibody, HRP-labeled secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.