Zebrafish Sod2 Antilichaam / Superoxide dismutase 2

Zebrafish Sod2 is an ortholog of the human SOD2 protein, with strong sequence and functional conservation. As in humans, Sod2 in zebrafish plays a vital role in protecting highly metabolic tissues such as the brain, heart, and muscles from oxidative damage. Mutations or reduced activity of Sod2 can lead to mitochondrial dysfunction and oxidative stress, contributing to developmental abnormalities and degenerative diseases. Currently, there are no confirmed isoforms of zebrafish Sod2. It is broadly expressed across tissues but is particularly abundant in cells with high energy demands. Zebrafish models deficient in Sod2 have been used to investigate the consequences of oxidative imbalance and to explore therapeutic approaches aimed at reducing mitochondrial stress. Antibodies targeting zebrafish Sod2 protein are important tools for studying mitochondrial antioxidant defense systems, oxidative signaling pathways, and stress responses. These antibodies can be utilized in western blot, immunohistochemistry, immunofluorescence, and ELISA to monitor Sod2 levels and localization in zebrafish tissues.

Western Blot: 0.5-1 µg/mL

Q6P980

Zebrafish

E. coli-derived zebrafish Sod2 recombinant protein (amino acids M1-K224) was used as the immunogen for the Zebrafish Sod2 antibody.

WB

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Sod2 antibody is available for research use only.

After reconstitution, the Zebrafish Sod2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Sod2 antibody should be determined by the researcher.

Western blot analysis of Sod2 protein using Zebrafish Sod2 antibody and 1) zebrafish head, 2) whole female zebrafish, 3) whole male zebrafish and 4) zebrafish embryo tissue lysate. Predicted molecular weight ~25 kDa.