Zebrafish Srp54 Antilichaam / Signaalherkenningsdeeltje 54 kDa eiwit

Zebrafish Srp54 is an ortholog of the human SRP54 protein and exhibits strong sequence and functional conservation. In both zebrafish and humans, Srp54 contains a GTP binding domain and an M domain that recognizes and interacts with hydrophobic signal sequences. These conserved domains highlight the importance of Srp54 in protein translocation processes that are essential for the development and survival of eukaryotic cells. The use of a Zebrafish Srp54 antibody allows researchers to detect and study the distribution and expression of Srp54 during early development and in various tissues. Such antibodies are valuable for western blot, immunohistochemistry, and immunofluorescence applications, providing insights into the role of the SRP pathway in protein targeting. A Zebrafish Srp54 antibody can also be used to analyze the effects of genetic mutations or experimental treatments on protein translocation and endoplasmic reticulum function. There are no confirmed isoforms of zebrafish Srp54, and its function appears to be highly conserved across vertebrate species. By using a high-quality Zebrafish Srp54 antibody, researchers can explore the essential roles of the signal recognition particle pathway in protein sorting and its relevance to human biology and disease.

Western Blot: 0.5-1 µg/mL

Q7ZVN5

Zebrafish

E. coli-derived zebrafish Srp54 recombinant protein (amino acids M1-K433) was used as the immunogen for the Zebrafish Srp54 antibody.

WB

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Srp54 antibody is available for research use only.

After reconstitution, the Zebrafish Srp54 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Srp54 antibody should be determined by the researcher.

Western blot analysis of Srp54 protein using Zebrafish Srp54 antibody and 1) zebrafish head, 2) whole female zebrafish, 3) whole male zebrafish and 4) zebrafish embryo tissue lysate. Predicted molecular weight ~56 kDa.