Zebravis Atoh7 Antilichaam / Lakritz

During zebrafish embryogenesis, atoh7 is expressed in retinal progenitor cells, and its activity initiates the genetic cascade required for RGC formation and optic nerve development. Mutations in atoh7, such as in the lakritz mutant, result in the complete absence of RGCs and a failure to form the optic nerve, making it a key model for studying retinal development, axonal pathfinding, and neuronal lineage commitment. Given its conserved function across vertebrates, zebrafish Atoh7 is widely used in research on eye development, stem cell differentiation, and regenerative medicine targeting visual system repair. It also serves as a molecular marker for early neurogenesis in the retina.

Immunohistochemistry (FFPE) : 2-5 µg/mL

Q8AW52

Zebrafish

E. coli-derived zebrafish Atoh7 recombinant protein (amino acids M1-L134) was used as the immunogen for the Zebrafish Atoh7 antibody.

IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Atoh7 antibody is available for research use only.

After reconstitution, the Zebrafish Atoh7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Atoh7 antibody should be determined by the researcher.

Localized to the Nucleoplasm, Flagellar centriole In addition localized to the Cytosol, Mid piece

IHC staining of zebrafish Atoh7 protein using Zebrafish Atoh7 antibody, HRP-labeled secondary and DAB substrate. Atoh7 was detected in a paraffin-embedded section of zebrafish eye tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.