Zebravis Atp6v1a Antilichaam

The Atp6v1a protein forms the core of the V1 domain, where it contributes to ATP hydrolysis, driving proton translocation across membranes via the V0 domain. This acidification is essential for maintaining cellular homeostasis, lysosomal function, and pH-dependent signaling pathways. In zebrafish (Danio rerio), Atp6v1a is highly conserved and broadly expressed during development, particularly in neural, renal, and gastrointestinal tissues. It serves as a model for studying V-ATPase function in vertebrate development, organogenesis, and disease models such as neurodegeneration and cancer.

Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL

Q7SY46

Zebrafish

An E.coli-derived zebrafish Atp6v1a recombinant protein (amino acids A37-D617) was used as the immunogen for the Zebrafish Atp6v1a antibody.

WB, IF

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Atp6v1a antibody is available for research use only.

After reconstitution, the Zebrafish Atp6v1a antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Atp6v1a antibody should be determined by the researcher.

Immunofluorescent staining of FFPE zebrafish embryo tissue with Zebrafish Atp6v1a antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH8 EDTA buffer for 20 min.