Zebravis Bmp2b Antilichaam / Botmorfogenetisch eiwit 2

During early embryogenesis, bmp2b is expressed in ventral tissues and functions as a key morphogen that establishes dorsoventral polarity by forming a signaling gradient. Loss-of-function mutations in bmp2b, such as the well-known swirl mutant, result in dorsalized embryos, underscoring its essential role in ventral tissue specification. Bmp2b also regulates the development of multiple organ systems, including the heart, fins, and skeletal elements, through its influence on proliferation, differentiation, and apoptosis of progenitor cells. Zebrafish Bmp2b is widely studied as a model for developmental signaling, stem cell biology, and tissue regeneration. It also provides a powerful system for investigating TGF-beta pathway modulation, signal transduction, and congenital malformations resulting from disrupted BMP signaling.

Western Blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

O93369

Zebrafish

E. coli-derived zebrafish Bmp2b recombinant protein (amino acids E27-D279) was used as the immunogen for the Zebrafish Bmp2b antibody.

WB, IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Bmp2b antibody is available for research use only.

After reconstitution, the Zebrafish Bmp2b antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Bmp2b antibody should be determined by the researcher.

IHC staining of FFPE zebrafish muscle tissue with Zebrafish Bmp2b antibody, HRP-labeled secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.