Zebravis Cyp19a1b Antilichaam/Aromatase

Cyp19a1b is predominantly expressed in radial glial cells in the zebrafish brain and is tightly regulated by estrogens and environmental factors. Its expression begins during early embryogenesis and continues throughout development and adulthood. Cyp19a1b is essential for brain development, neurogenesis, and the sexual differentiation of the brain. It also participates in the local modulation of estrogen signaling, which influences behavior, neural plasticity, and reproductive function. Due to its strong and specific expression in the brain, zebrafish Cyp19a1b is widely used as a sensitive biomarker for estrogenic activity and for studying the effects of endocrine-disrupting chemicals. It is also an important tool for investigating the roles of neuroestrogens in development, regeneration, and brain function.

Western Blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

Q5U870

Zebrafish

E. coli-derived zebrafish Cyp19a1b recombinant protein (amino acids Q230-E511) was used as the immunogen for the Zebrafish Cyp19a1b antibody.

WB, IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Cyp19a1b antibody is available for research use only.

After reconstitution, the Zebrafish Cyp19a1b antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Cyp19a1b antibody should be determined by the researcher.

IHC staining of FFPE zebrafish ovary tissue with Cyp19a1b antibody, HRP-labeled secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.