Zebravis Dgcr8 Antilichaam

MicroRNAs are short noncoding RNAs that regulate gene expression by targeting messenger RNAs for degradation or translational repression. Dgcr8 is crucial for maintaining proper levels of microRNAs, which are involved in numerous biological processes including early development, cell differentiation, neurogenesis, and organ formation. In zebrafish, Dgcr8 is expressed during early embryogenesis and is required for normal development of the brain, heart, and other organs. Loss of Dgcr8 function results in widespread defects due to disrupted microRNA biogenesis. Because of its evolutionary conservation and central role in RNA regulation, zebrafish Dgcr8 is widely used in studies of gene expression control, developmental biology, and disease models related to microRNA dysfunction.

Immunofluorescence: 5 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

A2BEG3

Zebrafish

E. coli-derived zebrafish Dgcr8 recombinant protein (amino acids K570-Q771) was used as the immunogen for the Zebrafish Dgcr8 antibody.

IF, IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Dgcr8 antibody is available for research use only.

After reconstitution, the Zebrafish Dgcr8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Dgcr8 antibody should be determined by the researcher.

Nucleus, Nucleolus

Immunofluorescent staining of Dgcr8 protein using Zebrafish Dgcr8 antibody (green) and zebrafish embryo tissue. HIER: steam section in pH8 EDTA buffer for 20 min.