Zebravis Stat3 Antilichaam

Activated through phosphorylation by Janus kinases (JAKs), Stat3 translocates to the nucleus, where it regulates target gene expression. In zebrafish, stat3 is dynamically expressed during embryogenesis and is required for processes such as gastrulation, organogenesis, and stem cell maintenance. It has been shown to be critical for liver and heart regeneration, as well as for innate immune responses to infection and injury. Due to its high conservation and broad functional relevance, zebrafish Stat3 serves as a powerful model for studying JAK/STAT signaling, immune regulation, oncogenesis, and regenerative biology. It is also widely used in research on inflammatory diseases, developmental disorders, and signal transduction mechanisms in vertebrates.

Western Blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL

A0A8M2BAX1

Zebrafish

E. coli-derived zebrafish Stat3 recombinant protein (amino acids K64-S335) was used as the immunogen for the Zebrafish Stat3 antibody.

WB, IHC-P, IF

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Stat3 antibody is available for research use only.

After reconstitution, the Zebrafish Stat3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Stat3 antibody should be determined by the researcher.

Cytoplasm, nucleus

IHC staining of FFPE zebrafish brain tissue with Zebrafish Stat3 antibody, HRP-labeled secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.