Zebravis Vangl2 Antilichaam / Vang-achtig eiwit 2

Zebrafish vangl2 is expressed early in development and is critical for establishing tissue polarity and directional cell migration. Mutations in vangl2-such as the well-studied trilobite mutant-lead to severe defects in neural tube formation, somite patterning, and organ positioning, making it a key model for understanding PCP signaling in vertebrates. Given its high conservation and pivotal role in developmental processes, zebrafish Vangl2 is widely used to study cell polarity, tissue architecture, and congenital disorders such as neural tube defects. It also provides valuable insights into cytoskeletal organization, cell-cell communication, and signal integration during vertebrate development.

Western Blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

Q8UVJ6

Zebrafish

E. coli-derived zebrafish Vangl2 recombinant protein (amino acids M1-D489) was used as the immunogen for the Zebrafish Vangl2 antibody.

WB, IHC-P

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Zebrafish Vangl2 antibody is available for research use only.

After reconstitution, the Zebrafish Vangl2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Zebrafish Vangl2 antibody should be determined by the researcher.

IHC staining of FFPE zebrafish skin tissue with Zebrafish Vangl2 antibody, HRP-labeled secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.